CD77 Antikörper
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- Target Alle CD77 Produkte
- CD77
- Reaktivität
- Human
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD77 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- The rat monoclonal antibody 38.13 recognizes CD77 (globotriaosylceramide Gb3), a neutral glycosphingolipid expressed mainly on the surface of B cell populations, such as germinal center B cells and Burkitt´s lymphoma cells.
- Aufreinigung
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
- Immunogen
- Daudi cell line (Burkitt´s lymphoma)
- Klon
- 38-13
- Isotyp
- IgM
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anti-CD77 antibody (FITC)
Reaktivität: Human FACS Wirt: Ratte Monoclonal 38-13 FITC
anti-CD77 antibody (PE)Reaktivität: Human FACS Wirt: Ratte Monoclonal 38-13 PE
anti-CD77 antibody (FITC)Reaktivität: Human FACS, IHC, IP Wirt: Maus Monoclonal 5B5 FITC
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 1 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- CD77
- Abstract
- CD77 Produkte
- Hintergrund
- CD77 (globotriaosylceramide Gb3), also known as the Pk blood group antigen, BLA (Burkitt´s lymphoma associated antigen), or CTH (ceramide trihexoside) is a neutral glycosphingolipid composed of three carbohydrate molecules linked to a lipid moiety in the cell membrane (Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer). It is expressed on germinal center B cells, Burkitt´s lymphoma cells, it can be induced on extrafolicular B cells and it is also found on endothelia and epithelia. CD77 may be involved in elimination of germinal center B cells that fail to produce high affinity antibodies, and serves also as receptor for shiga toxin and verotoxin.,globotriaosylceramide Gb3, Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer, P blood group
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