CD51/CD61 Antikörper
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- Target Alle CD51/CD61 (ITGAV/ITGB3) Antikörper anzeigen
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
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Reaktivität
- Human, Huhn
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD51/CD61 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex, that is expressed mainly on human osteoclasts, but also e.g. on placenta, or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.
- Keine Kreuzreaktivität
- Rind (Kuh), Schwein, Kaninchen
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Immunogen
- A cell suspension containing osteoclasts from osteoclastomas
- Klon
- 23C6
- Isotyp
- IgG1
- Top Product
- Discover our top product ITGAV/ITGB3 Primärantikörper
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anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody
ITGAV/ITGB3 Reaktivität: Human, Maus, Ratte FACS, WB, IF (cc), IF (p), IHC (fro), ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody (FITC)ITGAV/ITGB3 Reaktivität: Human FACS, IHC Wirt: Maus Monoclonal BV3 FITC
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody (PE)ITGAV/ITGB3 Reaktivität: Human, Huhn FACS Wirt: Maus Monoclonal 23C6 PE
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 Reaktivität: Human, Huhn, Kaninchen FACS, IHC, IHC (fro) Wirt: Maus Monoclonal 23C6 unconjugated
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 2-6 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- Andere Bezeichnung
- CD51/CD61 (ITGAV/ITGB3 Produkte)
- Synonyme
- CD51 antikoerper, MSK8 antikoerper, VNRA antikoerper, VTNR antikoerper, integrin subunit alpha V antikoerper, ITGAV antikoerper
- Hintergrund
- CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.,VNRA, MSK8, ITGB3, ITGAV, Integrin alpha5beta3, OFA, VR
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