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CD32/CD16 Antikörper

CD32/CD16 Reaktivität: Maus FACS, IP Wirt: Ratte Monoclonal 93 unconjugated
Produktnummer ABIN7013995
  • Target Alle CD32/CD16 Produkte
    CD32/CD16
    Reaktivität
    Maus
    Wirt
    • 54
    • 1
    • 1
    Ratte
    Klonalität
    • 51
    • 1
    • 1
    Monoklonal
    Konjugat
    • 16
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD32/CD16 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 10
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Spezifität
    The rat monoclonal antibody 93 recognizes a common extracellular epitope of murine CD16 (FcgammaRIII) and CD32 (FcgammaRII), the low affinity receptors for IgG.
    Aufreinigung
    Purified by protein-G affinity chromatography.
    Immunogen
    Murine pre-B cells
    Klon
    93
    Isotyp
    IgG2a lambda
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    CD32/CD16
    Andere Bezeichnung
    CD16/CD32 (CD32/CD16 Produkte)
    Hintergrund
    CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Unlike human, the murine protein is expressed only as a transmembrane isoform. Also CD32 (FcgammaRII) is a low affinity receptor for IgG, but its affinity is lower than that of CD16. These receptors are expressed on monocytes/macrophages, NK cells, granulocytes, mast cells, dendritic cells, and B cells. Their role is to mediate adaptive immune responses through binding the antibody-antigen immunocomplexes, but their effect on the particular cell differs according to the cell type.,CD16, CD32, FcgammaRIII, FCgammaRII, FCGR3, FCGR2
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