Rekombinanter G Protein-Coupled Receptor 119 Antikörper
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- Target Alle G Protein-Coupled Receptor 119 (GPR119) Antikörper anzeigen
- G Protein-Coupled Receptor 119 (GPR119)
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human, Maus, Ratte, Hund
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser G Protein-Coupled Receptor 119 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (IF), Blocking Peptide (BP)
- Verwendungszweck
- Anti-Glucose-dependent insulinotropic Receptor [Gipg013], Mouse IgG2a, lambda
- Spezifität
- The original has a Ki value of 7 nM and a Kd value of 6.8 nM for human GIPr.
- Kreuzreaktivität
- Hund, Maus, Ratte
- Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: scFv
- Aufreinigung
- Protein A affinity purified
- Immunogen
- Human GIPr.
- Klon
- Gipg013
- Isotyp
- IgG2a lambda
- Top Product
- Discover our top product GPR119 Primärantikörper
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- Applikationshinweise
- This antibody binds to GIPr, a GPCR expressed on pancreatic beta-cells, where activation leads to the release of insulin. Endogeonous ligands for the receptor include oleylethanolamide and lysophosphatidylcholine. The antibody acts as a competitive antagonist. In rat islets, the antibody inhibits GIP-induced secretion of insulin by up to 81 % .
- Kommentare
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This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- G Protein-Coupled Receptor 119 (GPR119)
- Andere Bezeichnung
- Glucose-dependent insulinotropic Receptor (GPR119 Produkte)
- Hintergrund
- GIPr
- UniProt
- Q8TDV5
- Pathways
- Hormone Transport, Peptide Hormone Metabolism
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