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Rekombinanter CD27 Antikörper

CD27 Reaktivität: Human, Maus, Ratte FACS, IF, IP, Act Wirt: Kaninchen Chimeric LG-3A10 unconjugated Recombinant Antibody
Produktnummer ABIN7072375
  • Target Alle CD27 Antikörper anzeigen
    CD27 (CD27 Molecule (CD27))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 188
    • 72
    • 51
    • 9
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 107
    • 88
    • 22
    • 11
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 141
    • 91
    • 1
    Chimeric
    Konjugat
    • 79
    • 24
    • 23
    • 15
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD27 Antikörper ist unkonjugiert
    Applikation
    • 151
    • 76
    • 49
    • 38
    • 33
    • 21
    • 17
    • 14
    • 13
    • 13
    • 10
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Activation (Act)
    Verwendungszweck
    Anti-CD27 [LG.3A10], Rabbit IgG, kappa
    Spezifität
    This antibody is specific for mouse CD27, which, as in the human system, is largely restricted to cells of the T cell lineage, and is expressed on the great majority of both αβ and γδ T lymphocytes, and thymocytes.
    Kreuzreaktivität
    Human, Ratte
    Produktmerkmale

    Original Species of Ab: Hamster, Armenian

    Original Format of Ab: IgG

    Aufreinigung
    Protein A affinity purified
    Immunogen
    This antibody was produced by injecting Armenian hamsters intraperitoneally with a mixture of two murine CD27 tag-expressing Armenian hamster fibroblast clones (AR0524 and AR0530) in Freund's adjuvant
    Klon
    LG-3A10
    Isotyp
    IgG kappa
    Top Product
    Discover our top product CD27 Primärantikörper
  • Applikationshinweise
    This antibody is specific for murine CD27, and has been used to assess the distribution of CD27 expression using IF, FC and IP analysis (Gravstein, 1995). Upon cross-linking, this antibody has been shown to induce a 4-fold increase in T cell proliferation in response to suboptimal stimulation with concanavalin A (Gravestein, 1995), indicating that this antibody is able to mimic ligand binding.
    Kommentare

    This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG format, for improved compatibility with existing reagents, assays and techniques.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % Proclin 300.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    CD27 (CD27 Molecule (CD27))
    Andere Bezeichnung
    CD27 (CD27 Produkte)
    Hintergrund
    TNFRS7, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7
    UniProt
    P41272
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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