Rekombinanter CD27 Antikörper
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- Target Alle CD27 Antikörper anzeigen
- CD27 (CD27 Molecule (CD27))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Chimeric
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Konjugat
- Dieser CD27 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Activation (Act)
- Verwendungszweck
- Anti-CD27 [LG.3A10], Rabbit IgG, kappa
- Spezifität
- This antibody is specific for mouse CD27, which, as in the human system, is largely restricted to cells of the T cell lineage, and is expressed on the great majority of both αβ and γδ T lymphocytes, and thymocytes.
- Kreuzreaktivität
- Human, Ratte
- Produktmerkmale
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Original Species of Ab: Hamster, Armenian
Original Format of Ab: IgG
- Aufreinigung
- Protein A affinity purified
- Immunogen
- This antibody was produced by injecting Armenian hamsters intraperitoneally with a mixture of two murine CD27 tag-expressing Armenian hamster fibroblast clones (AR0524 and AR0530) in Freund's adjuvant
- Klon
- LG-3A10
- Isotyp
- IgG kappa
- Top Product
- Discover our top product CD27 Primärantikörper
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- Applikationshinweise
- This antibody is specific for murine CD27, and has been used to assess the distribution of CD27 expression using IF, FC and IP analysis (Gravstein, 1995). Upon cross-linking, this antibody has been shown to induce a 4-fold increase in T cell proliferation in response to suboptimal stimulation with concanavalin A (Gravestein, 1995), indicating that this antibody is able to mimic ligand binding.
- Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG format, for improved compatibility with existing reagents, assays and techniques.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- CD27 (CD27 Molecule (CD27))
- Andere Bezeichnung
- CD27 (CD27 Produkte)
- Hintergrund
- TNFRS7, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7
- UniProt
- P41272
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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