Rekombinanter CD276 Antikörper (Extracellular Domain)
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- Target Alle CD276 Antikörper anzeigen
- CD276
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- AA 1-242, Extracellular Domain
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Chimeric
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Konjugat
- Dieser CD276 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Blocking Reagent (BR)
- Verwendungszweck
- Anti-B7-H3 [MJ18], Rabbit IgG, kappa
- Spezifität
- This antibody binds to mouse B7-H3 and does not react with other B7-family molecules.
- Produktmerkmale
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Original Species of Ab: Rat
Original Format of Ab: IgG1
- Aufreinigung
- Protein A affinity purified
- Immunogen
- This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1-242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.
- Klon
- MJ18
- Isotyp
- IgG kappa
- Top Product
- Discover our top product CD276 Primärantikörper
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- Applikationshinweise
- This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.
- Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- CD276
- Andere Bezeichnung
- B7-H3 (CD276 Produkte)
- Hintergrund
- CD276, B7H3
- UniProt
- Q8VE98
- Pathways
- Cancer Immune Checkpoints
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