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Rekombinanter CD276 Antikörper (Extracellular Domain)

CD276 Reaktivität: Maus FACS, BR Wirt: Kaninchen Chimeric MJ18 unconjugated Recombinant Antibody
Produktnummer ABIN7072434
  • Target Alle CD276 Antikörper anzeigen
    CD276
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 15
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-242, Extracellular Domain
    Reaktivität
    • 66
    • 37
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 47
    • 18
    • 10
    • 1
    Kaninchen
    Klonalität
    • 43
    • 33
    Chimeric
    Konjugat
    • 40
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD276 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 23
    • 23
    • 14
    • 13
    • 11
    • 8
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Blocking Reagent (BR)
    Verwendungszweck
    Anti-B7-H3 [MJ18], Rabbit IgG, kappa
    Spezifität
    This antibody binds to mouse B7-H3 and does not react with other B7-family molecules.
    Produktmerkmale

    Original Species of Ab: Rat

    Original Format of Ab: IgG1

    Aufreinigung
    Protein A affinity purified
    Immunogen
    This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1-242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.
    Klon
    MJ18
    Isotyp
    IgG kappa
    Top Product
    Discover our top product CD276 Primärantikörper
  • Applikationshinweise
    This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.
    Kommentare

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % Proclin 300.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    CD276
    Andere Bezeichnung
    B7-H3 (CD276 Produkte)
    Hintergrund
    CD276, B7H3
    UniProt
    Q8VE98
    Pathways
    Cancer Immune Checkpoints
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