Rekombinanter RHD Antikörper

Produktnummer ABIN7072535

Produktdetails anti-RHD Antikörper

Target: RHD (Rh Blood Group, D Antigen (RHD))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser RHD Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Verwendungszweck: Anti-Rhesus D antigen [D7C2], Rabbit IgG, lambda

Produktmerkmale:

Original Species of Ab: Human

Original Format of Ab: IgM

Aufreinigung: Protein A affinity purified

Immunogen: A Rh- volunteer blood donor (r/r) was injected with 5ml of Rh+ erythrocytes (R1/r) and the peripheral lymphocytes were isolated and transformed with 1 ml of culture supernatant of the EBV marmoset B96-8 cell line.

Klon: D7C2

Isotyp: IgG lambda

Anwendungsinformationen

Applikationshinweise: FC confirmed the binding of D7C2 to Rh D+ red cells in artifical mixtures (Edelman et al, 1997). The ADCC of D7C2 showed a percentage of 93 % lysis (Edelman et al, 1997). D7C2 has been expressed recombinantly using a baculovirus-insect cell expression system (Edelman et al, 1997).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgM format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu RHD

Target: RHD (Rh Blood Group, D Antigen (RHD))

Andere Bezeichnung: Rhesus D antigen (RHD Produkte)

Hintergrund: CD240D, RHXIII, Rh polypeptide 2, RhPII