APRIL antikoerper, PHAPI2 antikoerper, SSP29 antikoerper, 2410015B15Rik antikoerper, PAL31 antikoerper, PHAPI2a antikoerper, Ssp29 antikoerper, cb908 antikoerper, fa99a11 antikoerper, wu:fa28c10 antikoerper, wu:fa99a11 antikoerper, wu:fb40e12 antikoerper, zgc:77745 antikoerper, hLAMP-1 antikoerper, MGC80871 antikoerper, ANP32B antikoerper, MGC69373 antikoerper, SLAN antikoerper, acidic nuclear phosphoprotein 32 family member B antikoerper, acidic (leucine-rich) nuclear phosphoprotein 32 family, member B antikoerper, acidic nuclear phosphoprotein 32 family member B L homeolog antikoerper, acidic leucine-rich nuclear phosphoprotein 32 family member B antikoerper, ANP32B antikoerper, Anp32b antikoerper, anp32b antikoerper, anp32b.L antikoerper, LOC494442 antikoerper
Hintergrund
ANP32B is a member of the highly conserved acidic leucine-rich nuclear phosphoprotein 32 (ANP32) family. The ANP32 proteins have been implicated in a broad array of physiological processes, including cell differentiation, apoptotic cell death, and cell proliferation. ANP32B was identified as a novel direct substrate for caspase-3 and acted as a negative regulator for leukemic cell apoptosis. ANP32B controls the expression of the dendritic cell maturation factor CD83 by regulating the transport of its mRNA to the cytoplasm. It also modulates the activity of the transcription factor Kruppel-like factor 5 (KLF5).