ACTH Antikörper

Produktnummer ABIN7072981

Dieses Anti-ACTH-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ACTH in WB. Geeignet für Ratte und Maus.

Kurzübersicht für ACTH Antikörper (ABIN7072981)

Target: ACTH (Adrenocorticotropic hormone (ACTH))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACTH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACTH Antikörper

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse ACTH

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ACTH

Target: ACTH (Adrenocorticotropic hormone (ACTH))

Andere Bezeichnung: ACTH

Hintergrund: Pro-opiomelanocortin (POMC) is a precursor polypeptide with 266 amino acid residues. POMC is synthesized in the pituitary from the 285-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin (pre-POMC), by the removal of a 44-amino-acid-long signal peptide sequence during translation. POMC is cleaved to give rise to multiple peptide hormones(α-MSH, ACTH, β-Endorphin and [Met]enkephalin). Adrenocorticotropic hormone (ACTH, also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. It is also used as a medication and diagnostic agent.. ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress. Its principal effects are increased production and release of cortisol by the cortex of the adrenal gland. ACTH is also related to the circadian rhythm in many organisms.

Molekulargewicht: 30 kDa

Gen-ID: 18976

NCBI Accession: NP_001265510

UniProt: P01193

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity