alpha Actinin Antikörper

Produktnummer ABIN7073023

Produktdetails anti-alpha Actinin Antikörper

Target: alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha Actinin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human ACTN1

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:500-1:1000/1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu alpha Actinin

Target: alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))

Andere Bezeichnung: alpha Actinin (ACTN Produkte)

Synonyme: actinin, alpha 4 antikoerper, alpha-actinin antikoerper, ACTN4 antikoerper, ain1 antikoerper

Hintergrund: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.

Molekulargewicht: 103 kDa

Gen-ID: 109711

NCBI Accession: NP_001093

UniProt: P12814

Pathways: Cell-Cell Junction Organization, Negative Regulation of Transporter Activity