ABC31 antikoerper, EST90757 antikoerper, MLP2 antikoerper, MOAT-D antikoerper, MRP3 antikoerper, cMOAT2 antikoerper, 1700019L09Rik antikoerper, Mlp2 antikoerper, Mrp3 antikoerper, ATP binding cassette subfamily C member 3 antikoerper, ATP-binding cassette, sub-family C (CFTR/MRP), member 3 antikoerper, ABCC3 antikoerper, Abcc3 antikoerper
Hintergrund
The protein encoded by this gene is a member of the super family of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes.