B-Cell Linker Antikörper
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- Target Alle B-Cell Linker (BLNK) Antikörper anzeigen
- B-Cell Linker (BLNK)
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser B-Cell Linker Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse BLNK
- Top Product
- Discover our top product BLNK Primärantikörper
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anti-B-Cell Linker (BLNK) antibody
BLNK Reaktivität: Human, Maus WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 5G9 unconjugated
anti-B-Cell Linker (BLNK) (AA 65-314) antibodyBLNK Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 301-400) antibodyBLNK Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 1D7 unconjugated
anti-B-Cell Linker (BLNK) (C-Term) antibodyVerified BLNK Reaktivität: Human WB, ELISA, FACS, IF Wirt: Ziege Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 41-337) antibodyBLNK Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr96) antibodyBLNK Reaktivität: Human WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (N-Term) antibodyBLNK Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr96) antibodyBLNK Reaktivität: Human, Maus WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 150-178) antibodyBLNK Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18883 unconjugated
anti-B-Cell Linker (BLNK) (pTyr84) antibodyBLNK Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IHC/IF (M,R) 1:2500-1:5000/1:1500-1:2500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- B-Cell Linker (BLNK)
- Andere Bezeichnung
- BLNK (BLNK Produkte)
- Synonyme
- BLNK antikoerper, blnk antikoerper, MGC147045 antikoerper, BASH antikoerper, Bca antikoerper, Ly-57 antikoerper, Ly57 antikoerper, Lyw-57 antikoerper, SLP-65 antikoerper, AGM4 antikoerper, BLNK-S antikoerper, LY57 antikoerper, SLP65 antikoerper, bca antikoerper, B-cell linker antikoerper, B cell linker antikoerper, BLNK antikoerper, blnk antikoerper, Blnk antikoerper
- Hintergrund
- The function of BLNK was first illustrated in BLNK deficient DT40 cells, a chicken B-cell line, which exhibited an abrogated intracellular calcium mobilisation response and impaired activation of MAP kinases p38, JNK, and to a lesser degree ERK upon B-cell receptor (BCR) activation as compared to wild type DT40 cells. In knockout mice, BLNK deficiency results in a partial block in B-cell development, and in humans BLNK deficiency results in a much more profound block in B-cell development. Linker or adaptor proteins provide mechanisms by which receptors can amplify and regulate downstream effector proteins. The B-cell linker protein is essential for normal B-cell development.
- Gen-ID
- 17060
- NCBI Accession
- NP_032554
- UniProt
- Q9QUN3
- Pathways
- BCR Signaling
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