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BIRC3 Antikörper

BIRC3 Reaktivität: Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7073179
  • Target Alle BIRC3 Antikörper anzeigen
    BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
    Reaktivität
    • 67
    • 21
    • 5
    • 2
    Maus, Ratte
    Wirt
    • 60
    • 6
    • 2
    Kaninchen
    Klonalität
    • 63
    • 5
    Polyklonal
    Konjugat
    • 30
    • 7
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BIRC3 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 33
    • 23
    • 13
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse cIAP2
  • Applikationshinweise
    WB (M,R) 1: 500-1: 1000, IHC/IF (M,R) 1:1500-1:3000/1:750-1:1500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
    Andere Bezeichnung
    cIAP2 (BIRC3 Produkte)
    Synonyme
    AIP1 antikoerper, API2 antikoerper, CIAP2 antikoerper, HAIP1 antikoerper, HIAP1 antikoerper, MALT2 antikoerper, MIHC antikoerper, RNF49 antikoerper, c-IAP2 antikoerper, Api1 antikoerper, Api2 antikoerper, IAP1 antikoerper, IAP2 antikoerper, MIHB antikoerper, Birc2 antikoerper, HIAP2 antikoerper, MIAP1 antikoerper, MIAP2 antikoerper, cIAP1 antikoerper, cIAP2 antikoerper, cIAP-1 antikoerper, cIAP-2 antikoerper, AW107670 antikoerper, BIRC2 antikoerper, baculoviral IAP repeat containing 3 antikoerper, baculoviral IAP repeat-containing 3 antikoerper, baculoviral IAP repeat-containing protein 3 antikoerper, inhibitor of apoptosis protein-2 antikoerper, BIRC3 antikoerper, Birc3 antikoerper, LOC100399118 antikoerper, OpmnVgp074 antikoerper
    Hintergrund
    Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase dependent and caspase independent manner.
    Molekulargewicht
    67 kDa
    Gen-ID
    11796
    NCBI Accession
    NP_031490
    UniProt
    O08863
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades
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