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Caspase 3 Antikörper (cleaved)

Name: Caspase 3 Antikörper (cleaved)
Brand: antibodies-online
SKU: ABIN7073336
Price: 723.08 EUR
Availability: InStock

CASP3 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Immunohistochemistry of paraffin embedded rat spleen+LPS using c-caspase3 (ABIN7073336) at dilution of 1:500 (400x lens) (Caspase 3 Antikörper (cleaved))

IHC (p)

Immunofluorescence of paraffin embedded human colon cancer using c-caspase3 (ABIN7073336) at dilution of 1:500 (200x lens) (Caspase 3 Antikörper (cleaved))

IF (p)

Immunofluorescence of paraffin embedded human esophagus cancer using c-caspase3 (ABIN7073336) at dilution of 1:500 (400x lens) (Caspase 3 Antikörper (cleaved))

IF (p)

Immunofluorescence of paraffin embedded human stomcah cancer using c-caspase3 (ABIN7073336) at dilution of 1:500 (200x lens) (Caspase 3 Antikörper (cleaved))

11 Abbildungen

(5 Referenzen)

Produktnummer ABIN7073336

Datenblatt (PDF)

Target Alle Caspase 3 (CASP3) Antikörper anzeigen

Caspase 3 (CASP3)
Bindungsspezifität
19

16

16

14

12

12

9

9

9

8

8

7

6

6

5

5

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
cleaved
Reaktivität
205

117

71

17

11

10

8

8

7

5

5

4

3

3

2

2

1

1
Human, Maus, Ratte
Wirt
218

20

4

2

2
Kaninchen
Passende Sekundärantikörper
Klonalität
206

39
Polyklonal
Konjugat
151

18

17

7

7

5

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
Dieser Caspase 3 Antikörper ist unkonjugiert
Applikation
183

98

95

56

42

34

31

28

28

26

25

11

10

6

3

2

2

1

1

1

1

1

1
Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität

Human, Ratte

Aufreinigung

Affinity purification

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse caspase3

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Applikationshinweise

IHC/IF (H,M,R) 1:500-1:1000/1:500-1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C
Chen, Jin, Wang, Liu, Luo, Tian, Cai, Meng, Bi, Wang, Xie, Yu, Li, Dong, Cai, Jia, Wei, Jia: "GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling." in: JCI insight, Vol. 5, Issue 3, (2021) (PubMed).

Chang, Shang, Yuan, Guo, Wang: "EF24 exerts cytotoxicity against NSCLC via inducing ROS accumulation." in: Cancer cell international, Vol. 21, Issue 1, pp. 531, (2021) (PubMed).

Wang, Zheng, Che, Han, Li, Wang, Liu, Shi, Sun: "Protective effects of safranal on hypoxia/reoxygenation-induced injury in H9c2 cardiac myoblasts via the PI3K/AKT/GSK3β signaling pathway." in: Experimental and therapeutic medicine, Vol. 22, Issue 6, pp. 1400, (2021) (PubMed).

Elhadidy, Elmasry, Elsayed, El-Nablaway, Hamed, Elalfy, Rabei: "Modulation of COX-2 and NADPH oxidase-4 by alpha-lipoic acid ameliorates busulfan-induced pulmonary injury in rats." in: Heliyon, Vol. 7, Issue 10, pp. e08171, (2021) (PubMed).

Ma, Xu, Huang, Gao, Zhou, Li, Zhang: "Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation." in: Frontiers in physiology, Vol. 12, pp. 706359, (2021) (PubMed).
Target

Caspase 3 (CASP3)

Andere Bezeichnung

Caspase-3 (CASP3 Produkte)

Hintergrund

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).

Gen-ID

12367

NCBI Accession

NP_001271338

UniProt

P70677

Pathways

Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation