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Girdin Antikörper

CCDC88A Reaktivität: Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7073539
  • Target Alle Girdin (CCDC88A) Antikörper anzeigen
    Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
    Reaktivität
    • 56
    • 17
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 56
    Kaninchen
    Klonalität
    • 55
    • 1
    Polyklonal
    Konjugat
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Girdin Antikörper ist unkonjugiert
    Applikation
    • 36
    • 18
    • 14
    • 14
    • 14
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse Girdin
    Top Product
    Discover our top product CCDC88A Primärantikörper
  • Applikationshinweise
    IHC/IF (R) 1:1000-1:4000/1:500-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
    Andere Bezeichnung
    GIV (CCDC88A Produkte)
    Synonyme
    APE antikoerper, GIRDIN antikoerper, GIV antikoerper, GRDN antikoerper, HkRP1 antikoerper, KIAA1212 antikoerper, A430106J12Rik antikoerper, AI848406 antikoerper, Ape antikoerper, C130096N06Rik antikoerper, C330012F17Rik antikoerper, D130005J21Rik antikoerper, Girdin antikoerper, Giv antikoerper, Grdn antikoerper, Hkrp1 antikoerper, DKFZp459N1815 antikoerper, RGD1306694 antikoerper, coiled-coil domain containing 88A antikoerper, coiled coil domain containing 88A antikoerper, CCDC88A antikoerper, Ccdc88a antikoerper
    Hintergrund
    Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.
    Gen-ID
    108686
    NCBI Accession
    NP_789811
    UniProt
    Q5SNZ0
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