Girdin Antikörper
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- Target Alle Girdin (CCDC88A) Antikörper anzeigen
- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Girdin Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse Girdin
- Top Product
- Discover our top product CCDC88A Primärantikörper
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anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1401-1500) antibody
CCDC88A Reaktivität: Human ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) antibodyCCDC88A Reaktivität: Human, Maus ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (pTyr1765) antibodyCCDC88A Reaktivität: Human ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (pSer417) antibodyCCDC88A Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1571-1870) antibodyCCDC88A Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IHC/IF (R) 1:1000-1:4000/1:500-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
- Andere Bezeichnung
- GIV (CCDC88A Produkte)
- Hintergrund
- Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.
- Gen-ID
- 108686
- NCBI Accession
- NP_789811
- UniProt
- Q5SNZ0
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