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CYB561 Antikörper

CYB561 Reaktivität: Ratte IF, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7073661
  • Target Alle CYB561 Antikörper anzeigen
    CYB561 (Cytochrome B-561 (CYB561))
    Reaktivität
    • 19
    • 15
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 16
    • 3
    Kaninchen
    Klonalität
    • 16
    • 3
    Polyklonal
    Konjugat
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CYB561 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (IHC)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse Pyruvate Dehydrogenase E2
    Top Product
    Discover our top product CYB561 Primärantikörper
  • Applikationshinweise
    IHC/IF (R) 1:500-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    CYB561 (Cytochrome B-561 (CYB561))
    Andere Bezeichnung
    Pyruvate Dehydrogenase E2 (CYB561 Produkte)
    Synonyme
    CYB561A1 antikoerper, FRRS2 antikoerper, ECK1410 antikoerper, JW5224 antikoerper, MGC69260 antikoerper, zgc:193680 antikoerper, zgc:193701 antikoerper, ACYB-1 antikoerper, MBB18.18 antikoerper, MBB18_18 antikoerper, cytochrome B561-1 antikoerper, xcyt antikoerper, cytochrome b561 antikoerper, cytochrome b-561 antikoerper, cytochrome B561-1 antikoerper, cytochrome b561 L homeolog antikoerper, CYB561 antikoerper, cytb561 antikoerper, cybB antikoerper, LOC5576849 antikoerper, LOC5576850 antikoerper, Cyb561 antikoerper, cyb561 antikoerper, CYB-1 antikoerper, cyb561.L antikoerper, LOC100347599 antikoerper
    Hintergrund
    This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95 % of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure.
    Gen-ID
    235339
    UniProt
    Q8BMF4
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