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CYB561 Antikörper

CYB561 Reaktivität: Ratte IF, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7073661
  • Target Alle CYB561 Antikörper anzeigen
    CYB561 (Cytochrome B-561 (CYB561))
    Reaktivität
    • 12
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 9
    • 3
    Kaninchen
    Klonalität
    • 9
    • 3
    Polyklonal
    Konjugat
    • 12
    Dieser CYB561 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (IHC)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse Pyruvate Dehydrogenase E2
    Top Product
    Discover our top product CYB561 Primärantikörper
  • Applikationshinweise
    IHC/IF (R) 1:500-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    CYB561 (Cytochrome B-561 (CYB561))
    Andere Bezeichnung
    Pyruvate Dehydrogenase E2 (CYB561 Produkte)
    Hintergrund
    This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95 % of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure.
    Gen-ID
    235339
    UniProt
    Q8BMF4
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