DOCK2 Antikörper

Produktnummer ABIN7073706

Produktdetails anti-DOCK2 Antikörper

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse DOCK2

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu DOCK2

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Andere Bezeichnung: DOCK2 (DOCK2 Produkte)

Synonyme: AI662014 antikoerper, AW122239 antikoerper, CED-5 antikoerper, Hch antikoerper, MBC antikoerper, dedicator of cytokinesis 2 antikoerper, dedicator of cyto-kinesis 2 antikoerper, DOCK2 antikoerper, dock2 antikoerper, Dock2 antikoerper

Hintergrund: The DOCK2 gene encodes dedicator of cytokinesis 2 (DOCK 2), a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis. DOCK 2 participates in the cytoskeletal rearrangements that are required for lymphocyte migration in response of chemokines. DOCK 2 may also participate in IL-2 transcriptional activation through the activation of Rac 2. DOCK 2 contains one DHR-1 (CZH-1) domain, one DHR-2 (CZH-2) domain and one SH3 domain. The DHR-2 domain is a putative GEF activity mediator. The DOCK 2 protein also co-localizes with F-Actin, and demonstrates expression in several human tissues, with the highest levels observed in peripheral blood leukocytes, thymus, spleen and liver.

Molekulargewicht: 220 kDa

Gen-ID: 94176

NCBI Accession: NP_203538

UniProt: Q8C3J5