FOSB Antikörper

Produktnummer ABIN7073925

Produktdetails anti-FOSB Antikörper

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOSB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse FOSB

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu FOSB

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Andere Bezeichnung: Fos B (FOSB Produkte)

Synonyme: FOSB antikoerper, zgc:92354 antikoerper, AP-1 antikoerper, G0S3 antikoerper, GOS3 antikoerper, GOSB antikoerper, fra-2 antikoerper, FBJ murine osteosarcoma viral oncogene homolog B antikoerper, FosB proto-oncogene, AP-1 transcription factor subunit antikoerper, FBJ osteosarcoma oncogene B antikoerper, FOSB antikoerper, fosb antikoerper, Fosb antikoerper

Hintergrund: The FOS gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipperproteins that can dimerize with proteins of the JUN family (e.g., c-Jun, JunD), thereby forming thetranscription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. FosB and its truncated splice variants, ΔFosB and further truncated Δ2ΔFosB, are all involved in osteosclerosis, although Δ2ΔFosB lacks a knowntransactivation domain, in turn preventing it from affecting transcription through the AP-1 complex.

Molekulargewicht: 36 kDa

Gen-ID: 14282

NCBI Accession: NP_032062

UniProt: P13346