GTF2B Antikörper

Produktnummer ABIN7074034

Produktdetails anti-GTF2B Antikörper

Target: GTF2B (General Transcription Factor IIB (GTF2B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TFIIB

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1: 500-1: 1000, IHC/IF (H,M,R) 1:500-1:1500/1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu GTF2B

Target: GTF2B (General Transcription Factor IIB (GTF2B))

Andere Bezeichnung: TFIIB (GTF2B Produkte)

Synonyme: CG5193 antikoerper, Dmel\\CG5193 antikoerper, TFIIB antikoerper, Tfiib antikoerper, TfllB antikoerper, dTFIIB antikoerper, dTfIIB antikoerper, dmTFIIB antikoerper, gtf2b antikoerper, tf2b antikoerper, tfiib antikoerper, XLTFIIB antikoerper, TF2B antikoerper, wu:fc44c11 antikoerper, zgc:66258 antikoerper, Transcription factor IIB antikoerper, transcription initiation factor iib antikoerper, transcription initiation factor IIB antikoerper, transcription initiation factor IIB 2 antikoerper, Transcription initiation factor IIB antikoerper, general transcription factor 2B S homeolog antikoerper, general transcription factor 2B L homeolog antikoerper, general transcription factor IIB antikoerper, TfIIB antikoerper, CNF01950 antikoerper, tfb antikoerper, CC1G_14689 antikoerper, HacjB3_18813 antikoerper, HALXA_RS07110 antikoerper, HALXA_RS16310 antikoerper, tf2b antikoerper, LOC100283348 antikoerper, gtf2b.S antikoerper, gtf2b.L antikoerper, GTF2B antikoerper, gtf2b antikoerper, Gtf2b antikoerper

Hintergrund: General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA .Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex .Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle . Associates with chromatin to core promoter- specific regions .Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner,Modulates transcription start site selection . Exhibits also autoacetyltransferase activity that contributes to the activated transcription .

Molekulargewicht: 35 kDa

Gen-ID: 229906

NCBI Accession: NP_663521

UniProt: P62915