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GTF2B Antikörper

GTF2B Reaktivität: Human, Maus, Ratte WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7074034
  • Target Alle GTF2B Antikörper anzeigen
    GTF2B (General Transcription Factor IIB (GTF2B))
    Reaktivität
    • 76
    • 28
    • 13
    • 12
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    Human, Maus, Ratte
    Wirt
    • 62
    • 14
    Kaninchen
    Klonalität
    • 63
    • 13
    Polyklonal
    Konjugat
    • 42
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GTF2B Antikörper ist unkonjugiert
    Applikation
    • 56
    • 25
    • 13
    • 13
    • 11
    • 11
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human, Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse TFIIB
    Top Product
    Discover our top product GTF2B Primärantikörper
  • Applikationshinweise
    WB (H,M,R) 1: 500-1: 1000, IHC/IF (H,M,R) 1:500-1:1500/1:500-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    GTF2B (General Transcription Factor IIB (GTF2B))
    Andere Bezeichnung
    TFIIB (GTF2B Produkte)
    Hintergrund
    General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA .Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex .Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle . Associates with chromatin to core promoter- specific regions .Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner,Modulates transcription start site selection . Exhibits also autoacetyltransferase activity that contributes to the activated transcription .
    Molekulargewicht
    35 kDa
    Gen-ID
    229906
    NCBI Accession
    NP_663521
    UniProt
    P62915
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