GDF5 Antikörper
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- Target Alle GDF5 Antikörper anzeigen
- GDF5 (Growth Differentiation Factor 5 (GDF5))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GDF5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse GDF 5
- Top Product
- Discover our top product GDF5 Primärantikörper
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anti-Growth Differentiation Factor 5 (GDF5) (AA 358-495) antibody
GDF5 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 202-501) antibodyGDF5 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 382-501) antibodyGDF5 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (Internal Region) antibodyGDF5 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 28-127) antibodyGDF5 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1F4 unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 86-501) antibodyGDF5 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 13-41), (N-Term) antibodyGDF5 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB01877 unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 376-495) antibodyGDF5 Reaktivität: Maus ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 343-371), (C-Term) antibodyGDF5 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB31942 unconjugated
anti-Growth Differentiation Factor 5 (GDF5) (AA 350-450) antibodyGDF5 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB (H,M) 1:500-1:1000, IHC/IF (H,R) 1:200-1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- GDF5 (Growth Differentiation Factor 5 (GDF5))
- Andere Bezeichnung
- GDF 5 (GDF5 Produkte)
- Synonyme
- CDMP1 antikoerper, gdf antikoerper, gdf-5 antikoerper, GDF5 antikoerper, BDA1C antikoerper, BMP14 antikoerper, LAP4 antikoerper, OS5 antikoerper, SYM1B antikoerper, SYNS2 antikoerper, Cdmp-1 antikoerper, bp antikoerper, brp antikoerper, Cdmp1 antikoerper, growth differentiation factor 5 L homeolog antikoerper, growth differentiation factor 5 antikoerper, gdf5.L antikoerper, GDF5 antikoerper, Gdf5 antikoerper
- Hintergrund
- Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction . Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG . Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 .
- Molekulargewicht
- 55 kDa
- Gen-ID
- 14563
- NCBI Accession
- NP_032135
- UniProt
- P43027
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