CD74 Antikörper
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- Target Alle CD74 Antikörper anzeigen
- CD74 (HLA-DR-gamma (CD74))
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD74 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse CD74
- Top Product
- Discover our top product CD74 Primärantikörper
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- Applikationshinweise
- IHC/IF (M,R) 1:1000-1:4000/1:500-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- CD74 (HLA-DR-gamma (CD74))
- Andere Bezeichnung
- CD74 (CD74 Produkte)
- Hintergrund
- CD74, also known as the MHC class II associated invariant chain (Ii), is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is produced in molar excess over MHC class II and some of this is expressed by an unknown pathway on the cell surface independent of or in association with MHC class II molecules. The half life of CD74 on the cell surface is only 3 to 4 min after which it is internalized.
- Gen-ID
- 16149
- NCBI Accession
- NP_001036070
- UniProt
- P04441
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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