IP3 Receptor Antikörper

Produktnummer ABIN7074293

Produktdetails anti-IP3 Receptor Antikörper

Target: IP3 Receptor (ITP-R83A) (Inositol 1,4,5,-Tris-Phosphate Receptor (ITP-R83A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IP3 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human IP3 receptor

Anwendungsinformationen

Applikationshinweise: WB (H) 1: 500-1: 1000, IHC/IF (M,R) 1:500-1:1500/1:750-1:1500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu IP3 Receptor

Target: IP3 Receptor (ITP-R83A) (Inositol 1,4,5,-Tris-Phosphate Receptor (ITP-R83A))

Andere Bezeichnung: IP3 receptor (ITP-R83A Produkte)

Hintergrund: Inositol 1,4,5-trisphosphate receptor type 1 is a protein that in humans is encoded by the ITPR1 gene. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Molekulargewicht: 313 kDa

Gen-ID: 3708

NCBI Accession: NP_001093422

UniProt: Q14643

Pathways: Fc-epsilon Rezeptor Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma