ISR-alpha Antikörper

Produktnummer ABIN7074298

Produktdetails anti-ISR-alpha Antikörper

Target: ISR-alpha (Insulin Receptor alpha (ISR-alpha))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISR-alpha Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Insulin Receptor alpha

Anwendungsinformationen

Applikationshinweise: IHC: 1: 3000-1: 6000
Human, Mouse, Rat: Human, Mouse, Rat
Positive Tissue: endometrial cancer, esophagus cancer, uterus,small intestine

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ISR-alpha

Target: ISR-alpha (Insulin Receptor alpha (ISR-alpha))

Andere Bezeichnung: Insulin Receptor alpha (ISR-alpha Produkte)

Hintergrund: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

Gen-ID: 16337

UniProt: P15208