CD51 Antikörper
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- Target Alle CD51 (ITGAV) Antikörper anzeigen
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD51 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V
- Top Product
- Discover our top product ITGAV Primärantikörper
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- Applikationshinweise
- IHC/IF (H,M,R) 1:500-1:2000/1:500-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Andere Bezeichnung
- Integrin alpha V (ITGAV Produkte)
- Synonyme
- 1110004F14Rik antikoerper, 2610028E01Rik antikoerper, CD51 antikoerper, D430040G12Rik antikoerper, MSK8 antikoerper, VNRA antikoerper, VTNR antikoerper, Cd51 antikoerper, integrin subunit alpha V antikoerper, integrin alpha V antikoerper, ITGAV antikoerper, Itgav antikoerper
- Hintergrund
- The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling . ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling . ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.
- Gen-ID
- 16410
- NCBI Accession
- NP_032428
- UniProt
- P43406
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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