MANSC3 antikoerper, bA350J20.3 antikoerper, 1700034J19Rik antikoerper, 6330533B21 antikoerper, 9830160H19Rik antikoerper, wu:fj36e03 antikoerper, si:dkey-181i3.7 antikoerper, LDL receptor related protein 11 antikoerper, low density lipoprotein receptor-related protein 11 antikoerper, LRP11 antikoerper, Lrp11 antikoerper, lrp11 antikoerper
Hintergrund
LRP11 is a 500 amino acid single-pass type I membrane protein that exists as two alternatively spliced isoforms. LRP11 is encoded by a gene located on human chromosome 6q25.1. Chromosome 6 contains 170 million base pairs and comprises nearly 6 % of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.