AI461653 antikoerper, mal, T cell differentiation protein 2 antikoerper, mal, T-cell differentiation protein 2 (gene/pseudogene) antikoerper, mal, T-cell differentiation protein 2 antikoerper, Mal2 antikoerper, MAL2 antikoerper
Hintergrund
MAL2 (mal, T-cell differentiation protein 2) is a 176 amino acid multi-pass membrane protein that is associated with lipid rafts and contains one MARVEL domain. Expressed predominately in liver, kidney and lung, MAL2 functions as a member of the polarized machinery transport system and is required for transcytosis, a transporter pathway used to deliver membrane-bound cargo from perinuclear endosomes to the apical surface in a raft-dependent manner. Differential expression of MAL2 is associated with several cancers, including renal cell carcinoma and childhood leukemia, suggesting a role for MAL2 in tumorigensis.