MRPL12 Antikörper

Produktnummer ABIN7074638

Produktdetails anti-MRPL12 Antikörper

Target: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPL12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human MRPL12

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1: 500-1: 1000, IHC/IF (H) 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu MRPL12

Target: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Andere Bezeichnung: MRPL12 (MRPL12 Produkte)

Hintergrund: MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes, and is encoded by a nuclear gene. The protein forms a homodimer, localizes predominantly to mitochondria and binds to the large mitochondrial ribosomal subunit. It is required for CycD/Cdk4- induced cell growth. In addition, forming a ribosomal stalk with MRPL7, MRPL12 is required for the recruitment of translation elongation factors Tu and G to the large ribosomal subunit . It also a part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation and/or ribosome biogenesis during human mitochondrial gene expression.

Molekulargewicht: 21 kDa

Gen-ID: 56282

NCBI Accession: NP_081480

UniProt: Q9DB15