MAP3K3 Antikörper
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- Target Alle MAP3K3 Antikörper anzeigen
- MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MAP3K3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse MEKK3
- Top Product
- Discover our top product MAP3K3 Primärantikörper
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- Applikationshinweise
- WB (H,M,R) 1: 800-1: 1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
- Andere Bezeichnung
- MEKK3 (MAP3K3 Produkte)
- Synonyme
- MAPKKK3 antikoerper, MEKK3 antikoerper, AW548911 antikoerper, Mekk3 antikoerper, mKIAA4031 antikoerper, mitogen activated protein kinase kinase kinase 3 antikoerper, mitogen-activated protein kinase kinase kinase 3 antikoerper, Map3k3 antikoerper, MAP3K3 antikoerper, map3k3 antikoerper
- Hintergrund
- The mitogen-activated protein/ERK kinase kinase 3 (MEKK3) is a member of a family of MEKK/Ste11 serine/threonine protein kinases. One function of MEKK3 is to serve as an upstream regulatory kinase in the mitogen activated protein kinase cascade, however, it also plays a critical role in other signaling pathways. MEKK3 regulates several important functions including cell survival and proliferation. It is ubiquitously expressed in multiple tissues and has been found in complexes with scaffold proteins and other kinases.Cerebral cavernous malformations (CCMs) complex regulation of MEKK3 is essential during vertebrate heart development. MEKK3 signalling and KLF2/4 may be targeted to develop new CCM therapeutics.
- Molekulargewicht
- 78 kDa
- Gen-ID
- 26406
- NCBI Accession
- NP_036077
- UniProt
- Q61084
- Pathways
- MAPK Signalweg
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