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MYLK3 Antikörper

MYLK3 Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7074736
  • Target Alle MYLK3 Antikörper anzeigen
    MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))
    Reaktivität
    • 50
    • 34
    • 17
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 58
    Kaninchen
    Klonalität
    • 58
    Polyklonal
    Konjugat
    • 18
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MYLK3 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 28
    • 24
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse MYLK3/MLCK
    Top Product
    Discover our top product MYLK3 Primärantikörper
  • Applikationshinweise
    IHC/IF (M,R) 1:600-1:1200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))
    Andere Bezeichnung
    MYLK3/MLCK (MYLK3 Produkte)
    Synonyme
    MLCK antikoerper, MLCK2 antikoerper, caMLCK antikoerper, D830007F02Rik antikoerper, RGD1305801 antikoerper, myosin light chain kinase 3 antikoerper, MYLK3 antikoerper, Mylk3 antikoerper
    Hintergrund
    The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.
    Gen-ID
    213435
    NCBI Accession
    NP_001284541
    UniProt
    Q3UIZ8
    Pathways
    Regulation of Muscle Cell Differentiation
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