NLRP1 Antikörper
-
- Target Alle NLRP1 Antikörper anzeigen
- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
-
Reaktivität
- Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser NLRP1 Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse NLRP1
- Top Product
- Discover our top product NLRP1 Primärantikörper
-
-
- Applikationshinweise
- IHC/IF (M,R) 1:500-1:2000/1:250-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
-
- Target
- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
- Andere Bezeichnung
- NLRP1 (NLRP1 Produkte)
- Synonyme
- CARD7 antikoerper, CIDED antikoerper, CLR17.1 antikoerper, DEFCAP antikoerper, DEFCAP-L/S antikoerper, NAC antikoerper, NALP1 antikoerper, PP1044 antikoerper, SLEV1 antikoerper, VAMAS1 antikoerper, NLR family pyrin domain containing 1 antikoerper, NLRP1 antikoerper, Nlrp1 antikoerper
- Hintergrund
- NACHT, LRR and PYD domains-containing protein 1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. The NLRP1 protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
- Gen-ID
- 195046
- NCBI Accession
- NP_001004142
- UniProt
- Q2LKU9
- Pathways
- Positive Regulation of Endopeptidase Activity, Inflammasome
-