P2RY12 Antikörper

Produktnummer ABIN7075321

Produktdetails anti-P2RY12 Antikörper

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P2RY12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse P2Y12

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1:250-1:500, IHC/IF (M,R) 1:1000-1:3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu P2RY12

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Andere Bezeichnung: P2Y12 (P2RY12 Produkte)

Synonyme: 2900079B22Rik antikoerper, 4921504D23Rik antikoerper, P2Y12 antikoerper, ADPG-R antikoerper, BDPLT8 antikoerper, HORK3 antikoerper, P2T(AC) antikoerper, P2Y(12)R antikoerper, P2Y(AC) antikoerper, P2Y(ADP) antikoerper, P2Y(cyc) antikoerper, SP1999 antikoerper, P2y12 antikoerper, purinergic receptor P2Y, G-protein coupled 12 antikoerper, purinergic receptor P2Y12 antikoerper, P2ry12 antikoerper, P2RY12 antikoerper

Hintergrund: The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. Human platelets express two G protein-coupled nucleotide receptors, P2Y1 and P2Y12. P2Y12 is a receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. P2Y12 is an integral membrane protein involved in platelet aggregation. It is highly expressed in platelets, with lower levels in the brain, lung, appendix, pituitary and adrenal gland.

Molekulargewicht: 50 kDa

Gen-ID: 70839

NCBI Accession: NP_081847

UniProt: Q9CPV9