RRAGB Antikörper

Produktnummer ABIN7075379

Produktdetails anti-RRAGB Antikörper

Target: RRAGB (Ras-Related GTP Binding B (RRAGB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRAGB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse RRAGB

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:2000-1:4000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu RRAGB

Target: RRAGB (Ras-Related GTP Binding B (RRAGB))

Andere Bezeichnung: RRAGB (RRAGB Produkte)

Hintergrund: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.

Molekulargewicht: 43 kDa

Gen-ID: 245670

NCBI Accession: NP_001004154

UniProt: Q6NTA4