RMND5A Antikörper

Produktnummer ABIN7075401

Produktdetails anti-RMND5A Antikörper

Target: RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RMND5A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse RMND5A

Anwendungsinformationen

Applikationshinweise: IHC/IF (M,R) 1:1500-1:3000/1:600-1:1200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu RMND5A

Target: RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))

Andere Bezeichnung: RMND5A (RMND5A Produkte)

Synonyme: CTLH antikoerper, GID2 antikoerper, GID2A antikoerper, RMD5 antikoerper, p44CTLH antikoerper, 1110007A06Rik antikoerper, AJ237586 antikoerper, AW125795 antikoerper, Gid2 antikoerper, MTA.D02.090 antikoerper, required for meiotic nuclear division 5 homolog A antikoerper, RMND5A antikoerper, Rmnd5a antikoerper

Hintergrund: Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.

Gen-ID: 68477

NCBI Accession: NP_077250

UniProt: Q80YQ8