ARHGAP17 Antikörper

Produktnummer ABIN7075416

Produktdetails anti-ARHGAP17 Antikörper

Target: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse ARHGAP17

Anwendungsinformationen

Applikationshinweise: WB (M) 1:250-1:500, IHC/IF (R) 1:500-1:1500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ARHGAP17

Target: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Andere Bezeichnung: ARHGAP17 (ARHGAP17 Produkte)

Hintergrund: ARHGAP17 is a Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. It specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. RHGAP17 participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

Molekulargewicht: 81 kDa

Gen-ID: 70497

NCBI Accession: NP_001116112

UniProt: Q3UIA2