RNF7 Antikörper

Produktnummer ABIN7075471

Produktdetails anti-RNF7 Antikörper

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF7 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse RNF7

Anwendungsinformationen

Applikationshinweise: IHC/IF (H,M,R) 1:500-1:2000/1:500-1:3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu RNF7

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Andere Bezeichnung: RNF7 (RNF7 Produkte)

Hintergrund: The RNF7 is probable a component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.

Gen-ID: 19823

NCBI Accession: NP_001298064

UniProt: Q9WTZ1

Pathways: Positive Regulation of Endopeptidase Activity