SMYD2A Antikörper
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- Target Alle SMYD2A Antikörper anzeigen
- SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMYD2A Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse SMYD2
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- Applikationshinweise
- IHC/IF (M,R) 1:1000-1:4000/1:1000-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
- Andere Bezeichnung
- KMT3C/SMYD2 (SMYD2A Produkte)
- Hintergrund
- Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53.
- Gen-ID
- 226830
- NCBI Accession
- NP_081072
- UniProt
- Q8R5A0
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