SIN3A Antikörper
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- Target Alle SIN3A Antikörper anzeigen
- SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SIN3A Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse mSin3A
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- Applikationshinweise
- IHC/IF (M,R) 1:100-1:200/1:100-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
- Andere Bezeichnung
- mSin3A (SIN3A Produkte)
- Synonyme
- AW553200 antikoerper, Sin3 antikoerper, mKIAA4126 antikoerper, mSin3A antikoerper, zgc:162128 antikoerper, SIN3A antikoerper, SIN3 transcription regulator family member A antikoerper, transcriptional regulator, SIN3A (yeast) antikoerper, paired amphipathic helix protein Sin3a antikoerper, SIN3 transcription regulator family member Aa antikoerper, SIN3A antikoerper, Sin3a antikoerper, LOC100641919 antikoerper, sin3aa antikoerper, LOC100439524 antikoerper
- Hintergrund
- The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. And It acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.
- Gen-ID
- 20466
- NCBI Accession
- NP_001103820
- UniProt
- Q60520
- Pathways
- Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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