Kcc2 antikoerper, KCC2 antikoerper, mKIAA1176 antikoerper, solute carrier family 12 member 5 antikoerper, solute carrier family 12, member 5 antikoerper, SLC12A5 antikoerper, Slc12a5 antikoerper
Hintergrund
KCC2, encoded by SLC12A5, is a neuron-specific K+-Cl- cotransporter that is essential for Cl- homeostasis and inhibitory synaptic transmission in brain. KCC2 is expressed at high levels in neurons throughout the nervous system. KCC2 deletion caused animal death. Alterations of KCC2 have been linked to neuropathic pain, temporal lobe epilepsy, and other diseases.