SYTL2 Antikörper

Produktnummer ABIN7075797

Produktdetails anti-SYTL2 Antikörper

Target: SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYTL2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse SYTL2/SLP2

Anwendungsinformationen

Applikationshinweise: IHC/IF (H,M,R) 1:800-1:1600/1:600-1:1200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu SYTL2

Target: SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))

Andere Bezeichnung: SYTL2/SLP2 (SYTL2 Produkte)

Synonyme: AI266830 antikoerper, Slp2 antikoerper, Slp2-a antikoerper, Slp2-b antikoerper, Slp2-c antikoerper, Slp2-d antikoerper, mKIAA1597 antikoerper, CHR11SYT antikoerper, EXO4 antikoerper, SGA72M antikoerper, SLP2 antikoerper, SLP2A antikoerper, synaptotagmin-like 2 antikoerper, synaptotagmin like 2 antikoerper, Sytl2 antikoerper, SYTL2 antikoerper

Hintergrund: Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.

Gen-ID: 83671

NCBI Accession: NP_001035174

UniProt: Q99N50