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TBC1D7 Antikörper

TBC1D7 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7075849
  • Target Alle TBC1D7 Antikörper anzeigen
    TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
    Reaktivität
    • 25
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 23
    • 2
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser TBC1D7 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 16
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human, Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse TBC1D7
    Top Product
    Discover our top product TBC1D7 Primärantikörper
  • Applikationshinweise
    WB (H,M,R) 1: 500- 1: 1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
    Andere Bezeichnung
    TBC1D7 (TBC1D7 Produkte)
    Synonyme
    PIG51 antikoerper, TBC7 antikoerper, dJ257A7.3 antikoerper, 2610009C09Rik antikoerper, TBC1 domain family member 7 antikoerper, TBC1 domain family, member 7 antikoerper, TBC1D7 antikoerper, Tbc1d7 antikoerper
    Hintergrund
    TBC1 domain family member 7 (TBC1D7, TBC7) belongs to a family of TBC (Tre-2/Bub2/Cdc16) containing proteins that function as GTPase-activating proteins (GAPs) . TBC1D7 was initially identified as a novel binding protein within the TSC1-TSC2 complex, where it was thought to associate with TSC1 . Additional research indicates that TBC1D7 is a third subunit of the TSC1-TSC2 complex that possesses Rheb-GAP activity and signals upstream of mTORC1. Knockdown of TBC1D7 limits the association between TSC1 and TSC2, resulting in reduced Rheb-GAP activity and increased mTORC1 signaling . Mutations in the corresponding TBC1D7 gene result in increased mTORC1 signaling, delayed autophagy, and are associated with intellectual disability (ID) and macrocrania.
    Molekulargewicht
    36 kDa
    Gen-ID
    67046
    NCBI Accession
    NP_001239568
    UniProt
    Q9D0K0
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