RAP1 Antikörper
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- Target Alle RAP1 (TERF2IP) Antikörper anzeigen
- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse RAP1
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- Applikationshinweise
- WB (H,M) 1:500-1:1000, IHC/IF (M,R) 1:1000-1:3000/1:500-1:3000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
- Andere Bezeichnung
- RAP1 (TERF2IP Produkte)
- Synonyme
- DRIP5 antikoerper, RAP1 antikoerper, Rap1 antikoerper, cRAP1 antikoerper, TERF2 interacting protein antikoerper, telomeric repeat binding factor 2, interacting protein antikoerper, TERF2IP antikoerper, Terf2ip antikoerper
- Hintergrund
- Telomeric repeat-binding factor 2-interacting protein 1 acts both as a regulator of telomere function and as a transcription regulator. it is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length.
- Molekulargewicht
- 46 kDa
- Gen-ID
- 57321
- UniProt
- Q91VL8
- Pathways
- Zellzyklus, Telomere Maintenance
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