TCF7 Antikörper
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- Target Alle TCF7 Antikörper anzeigen
- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TCF7 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse TCF7
- Top Product
- Discover our top product TCF7 Primärantikörper
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- Applikationshinweise
- IHC/IF (M,R) 1:600-1:1200/1:600-1:1200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
- Andere Bezeichnung
- TCF7 (TCF7 Produkte)
- Hintergrund
- TCF7 (transcriptional factor 7) is a transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ and CD8+ immature thymocytes. Isoforms for TCF7 lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. TCF7 binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. It may also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3, and TLE4 repress transactivation mediated by TCF7 and CTNNB1.
- Gen-ID
- 21414
- NCBI Accession
- NP_001300910
- UniProt
- Q00417
- Pathways
- WNT Signalweg
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