This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Miao, Ding, Zou, Yang, Yang, Zhang, Li, Zhou, Zhang, Zhang, Du, Jiang, Zhou: "Inhibition of MyD88 by a novel inhibitor reverses two-thirds of the infarct area in myocardial ischemia and reperfusion injury." in: American journal of translational research, Vol. 12, Issue 9, pp. 5151-5169, (2020) (PubMed).
Target
Cardiac Troponin T2 (cTnT)
(Cardiac Troponin T (cTnT))
As part of the Troponin complex, the function of cTnT is to regulate muscle contraction. The N-terminal region of TnT that strongly binds actin most likely moves with Tm and actin during strong myosin crossbridge binding and force generation. This region is likely involved in the transduction of cooperativity down the thin filament. The C-terminal region of TnT constitutes part of the globular troponin complex domain, and participates in employing the calcium sensitivity of strong myosin crossbridge binding to the thin filament.