ube3a Antikörper
Kurzübersicht für ube3a Antikörper (ABIN7076105)
Target
Alle ube3a Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse UBE3A
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Applikationshinweise
- IHC/IF (H,M,R) 1:100-1:500/1:500-1:1300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
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Andere Bezeichnung
- UBE3A
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Hintergrund
- UBE3A (ubiquitin-protein ligase E3A, AKA E6AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Additionally, UBE3A may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins.
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Gen-ID
- 22215
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NCBI Accession
- NP_035798
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UniProt
- O08759
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
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