ube3a Antikörper
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- Target Alle ube3a Antikörper anzeigen
- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ube3a Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse UBE3A
- Top Product
- Discover our top product ube3a Primärantikörper
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- Applikationshinweise
- IHC/IF (H,M,R) 1:100-1:500/1:500-1:1300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
- Andere Bezeichnung
- UBE3A (ube3a Produkte)
- Hintergrund
- UBE3A (ubiquitin-protein ligase E3A, AKA E6AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Additionally, UBE3A may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins.
- Gen-ID
- 22215
- NCBI Accession
- NP_035798
- UniProt
- O08759
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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