UAP1L1 Antikörper

Produktnummer ABIN7076143

Produktdetails anti-UAP1L1 Antikörper

Target: UAP1L1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1-Like 1 (UAP1L1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UAP1L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse UAP1L1

Anwendungsinformationen

Applikationshinweise: WB (M) 1:2000- 1:4000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu UAP1L1

Target: UAP1L1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1-Like 1 (UAP1L1))

Andere Bezeichnung: UAP1L1 (UAP1L1 Produkte)

Synonyme: RP11-229P13.18 antikoerper, 5730445F03Rik antikoerper, zgc:56509 antikoerper, UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 antikoerper, UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 antikoerper, UDP-N-acetylglucosamine pyrophosphorylase 1, like 1 antikoerper, UAP1L1 antikoerper, Uap1l1 antikoerper, uap1l1 antikoerper

Hintergrund: UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.

Molekulargewicht: 57 kDa

Gen-ID: 227620

NCBI Accession: NP_001028465

UniProt: Q3TW96