ZNF746 Antikörper
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- Target Alle ZNF746 Antikörper anzeigen
- ZNF746 (Zinc Finger Protein 746 (ZNF746))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZNF746 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse PARIS
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- Applikationshinweise
- WB (H) 1:500-1:1000, IHC/IF (M,R) 1:1500-1:3000/1:1500-1:3000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- ZNF746 (Zinc Finger Protein 746 (ZNF746))
- Andere Bezeichnung
- PARIS (ZNF746 Produkte)
- Synonyme
- PARIS antikoerper, 2810407L07Rik antikoerper, AI317225 antikoerper, Znf746 antikoerper, RGD1306209 antikoerper, zinc finger protein 746 antikoerper, ZNF746 antikoerper, Zfp746 antikoerper
- Hintergrund
- ZNF746, also named as PARIS, which belongs to the krueppel C2H2-type zinc-finger protein family. ZNF746 mainly localizes to the cytoplasm and probably translocates to the nucleus to repress selected genes. ZNF746 as a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. ZNF746 may act as a downstream effector of PRKN and contribute to neurodegeneration in Parkinson disease cases caused by defects in PRKN.
- Molekulargewicht
- 100 kDa
- Gen-ID
- 69228
- NCBI Accession
- NP_001156947
- UniProt
- Q3U133
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