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ZNF746 Antikörper

ZNF746 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7076272
  • Target Alle ZNF746 Antikörper anzeigen
    ZNF746 (Zinc Finger Protein 746 (ZNF746))
    Reaktivität
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 5
    • 1
    Kaninchen
    Klonalität
    • 5
    • 1
    Polyklonal
    Konjugat
    • 6
    Dieser ZNF746 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse PARIS
  • Applikationshinweise
    WB (H) 1:500-1:1000, IHC/IF (M,R) 1:1500-1:3000/1:1500-1:3000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    ZNF746 (Zinc Finger Protein 746 (ZNF746))
    Andere Bezeichnung
    PARIS (ZNF746 Produkte)
    Synonyme
    PARIS antikoerper, 2810407L07Rik antikoerper, AI317225 antikoerper, Znf746 antikoerper, RGD1306209 antikoerper, zinc finger protein 746 antikoerper, ZNF746 antikoerper, Zfp746 antikoerper
    Hintergrund
    ZNF746, also named as PARIS, which belongs to the krueppel C2H2-type zinc-finger protein family. ZNF746 mainly localizes to the cytoplasm and probably translocates to the nucleus to repress selected genes. ZNF746 as a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. ZNF746 may act as a downstream effector of PRKN and contribute to neurodegeneration in Parkinson disease cases caused by defects in PRKN.
    Molekulargewicht
    100 kDa
    Gen-ID
    69228
    NCBI Accession
    NP_001156947
    UniProt
    Q3U133
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