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CD4 Antikörper (FITC)

GMP Grade CD4 Reaktivität: Human, Rhesusaffen, Cynomolgus FACS Wirt: Maus Monoclonal SK3 FITC
Produktnummer ABIN7076564
  • Target Alle CD4 Antikörper anzeigen
    CD4
    Reaktivität
    • 347
    • 223
    • 122
    • 48
    • 24
    • 21
    • 19
    • 19
    • 17
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 9
    • 9
    • 9
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rhesusaffen, Cynomolgus
    Wirt
    • 364
    • 146
    • 134
    • 3
    • 3
    • 1
    Maus
    Klonalität
    • 506
    • 137
    • 5
    Monoklonal
    Konjugat
    • 209
    • 73
    • 65
    • 49
    • 38
    • 16
    • 13
    • 13
    • 11
    • 10
    • 9
    • 9
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser CD4 Antikörper ist konjugiert mit FITC
    Applikation
    • 513
    • 202
    • 139
    • 118
    • 97
    • 78
    • 73
    • 42
    • 39
    • 36
    • 31
    • 29
    • 17
    • 10
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Verwendungszweck
    CD4 FITC Antibody
    Produktmerkmale
    The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD4 contains four extracellular Ig-like domains (D1-D4). The epitope for SK3 is located within the D3 domain of the protein, which has a structure resembling an Ig variable domain. Expression of CD4 is observed in subsets of T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. Binding of SK3 antibody blocks HIV infection through CD4 and also blocks the mixed lymphocyte reaction (MLR).
    Aufreinigung
    Purified
    Reinheit
    >95 %
    Güteklasse
    GMP Grade
    Immunogen
    Human peripheral blood T cell
    Klon
    SK3
    Isotyp
    IgG1, kappa
    Top Product
    Discover our top product CD4 Primärantikörper
  • Applikationshinweise
    FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    2-8°C, Conjugated antibodies should never be frozen.
  • Target
    CD4
    Andere Bezeichnung
    CD4 (CD4 Produkte)
    Gen-ID
    920
    NCBI Accession
    NM_000616
    UniProt
    P01730
    Pathways
    T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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