Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ZAP70 Antikörper (AA 247-382) (PE)

GMP Grade ZAP70 Reaktivität: Human FACS Wirt: Maus Monoclonal C-D12 PE
Produktnummer ABIN7077616
  • Target Alle ZAP70 Antikörper anzeigen
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    Bindungsspezifität
    • 34
    • 34
    • 25
    • 20
    • 20
    • 16
    • 14
    • 10
    • 9
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 247-382
    Reaktivität
    • 276
    • 129
    • 49
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Human
    Wirt
    • 205
    • 67
    • 2
    • 2
    • 1
    Maus
    Klonalität
    • 198
    • 78
    Monoklonal
    Konjugat
    • 135
    • 16
    • 16
    • 13
    • 11
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser ZAP70 Antikörper ist konjugiert mit PE
    Applikation
    • 194
    • 118
    • 102
    • 67
    • 53
    • 53
    • 45
    • 24
    • 23
    • 22
    • 13
    • 12
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Verwendungszweck
    Zap70 PE Antibody
    Produktmerkmale
    The clone C-D12, a mouse monoclonal antibody selectively binds with the 70kd tyrosine phosphoprotein known as ZAP-70 which is usually associated with the ζ-chain CD3-receptor-associated protein tyrosine kinase (PTK). It is a member of the Syk family that is localized exclusively to the cytosol of T cells and natural killer (NK) cells and  is required for their cellular activation. It is generally considered the T-lymphocyte counterpart of Syk, a B-cell receptor (BCR)-associated kinase that belongs to the same PTK family and plays a similar role in the antigen receptor signaling in the B-lineage cells. It facilitates the upregulation of Fas ligand in activation-induced T cell apoptosis. ZAP-70 expression plays an important role in the clinical diagnosis of various types of hematologic malignancies.
    Aufreinigung
    Purified
    Reinheit
    >95 %
    Güteklasse
    GMP Grade
    Immunogen
    Recombinant fragment of human ZAP70 protein (around aa 247-382)
    Klon
    C-D12
    Isotyp
    IgG1, kappa
    Top Product
    Discover our top product ZAP70 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    2-8°C, Conjugated antibodies should never be frozen.
  • Target
    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
    Andere Bezeichnung
    Zap70 (ZAP70 Produkte)
    Synonyme
    SRK antikoerper, STCD antikoerper, STD antikoerper, TZK antikoerper, ZAP-70 antikoerper, 70kDa antikoerper, AI327364 antikoerper, Srk antikoerper, mrtle antikoerper, mur antikoerper, zap70 antikoerper, MGC80670 antikoerper, MGC88962 antikoerper, ZAP70 antikoerper, zgc:110383 antikoerper, zeta chain of T-cell receptor associated protein kinase 70 antikoerper, putative tyrosine-protein kinase zap-70 antikoerper, zeta-chain (TCR) associated protein kinase antikoerper, zeta chain of T cell receptor associated protein kinase 70 antikoerper, zeta-chain (TCR) associated protein kinase 70kDa antikoerper, zeta chain of T cell receptor associated protein kinase 70kDa L homeolog antikoerper, zeta chain of T cell receptor associated protein kinase 70kDa antikoerper, tyrosine-protein kinase ZAP-70 antikoerper, ZAP70 antikoerper, Smp_149470 antikoerper, Zap70 antikoerper, zap70.L antikoerper, zap70 antikoerper, LOC707555 antikoerper, LOC100342021 antikoerper, LOC100390922 antikoerper, LOC100542877 antikoerper
    Gen-ID
    7535
    UniProt
    P43403
    Pathways
    T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
Sie sind hier:
Kundenservice