VAPB Antikörper (AA 51-150)

Produktnummer ABIN705536

Produktdetails anti-VAPB Antikörper

Target: VAPB (VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C (VAPB))

Bindungsspezifität: AA 51-150

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VAPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VAPB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu VAPB

Target: VAPB (VAMP (Vesicle-Associated Membrane Protein)-Associated Protein B and C (VAPB))

Andere Bezeichnung: VAPB (VAPB Produkte)

Synonyme: ALS8 antikoerper, VAMP-B antikoerper, VAP-B antikoerper, AI225786 antikoerper, AI840687 antikoerper, AI848259 antikoerper, D2Abb2e antikoerper, R75548 antikoerper, VAP33b antikoerper, Vamp33b antikoerper, fc05d09 antikoerper, wu:fa96d05 antikoerper, wu:fc05d09 antikoerper, zgc:66045 antikoerper, vamp-b antikoerper, vamp-c antikoerper, vap-b antikoerper, vap-c antikoerper, vapb antikoerper, VAMP associated protein B and C antikoerper, vesicle-associated membrane protein-associated protein B/C antikoerper, vesicle-associated membrane protein, associated protein B and C antikoerper, VAMP (vesicle-associated membrane protein)-associated protein B and C antikoerper, VAMP (vesicle-associated membrane protein)-associated protein B and C L homeolog antikoerper, VAPB antikoerper, Tsp_07972 antikoerper, Vapb antikoerper, vapb antikoerper, vapb.L antikoerper

Hintergrund:

Synonyms: ALS 8, ALS8, D2Abb2e, UNQ484/PRO983, Vamp 33b, VAMP associated 33 kDa protein, VAMP associated protein B and C, VAMP associated protein B, VAMP associated protein B/C, VAMP associated protein C, VAMP B, VAMP B VAMP C, VAMP B/VAMP C, VAMP C, VAMP vesicle associated membrane protein associated protein B and C, Vamp33b, VAMPB, VAMPB/VAMPC, VAMPC, VAP 33b, VAP B, VAP B/VAP C, VAP C, VAP33b, VAPB/VAPC, VAPC antibody Vesicle associated membrane protein associated protein B and C, Vesicle associated membrane protein associated protein B/C, VAPB_HUMAN.

Background: VAPB contains 1 MSP domain and it may play a role in vesicle trafficking. Defects in VAPB are a cause of proximal adult autosomal dominant spinal muscular atrophy [MIM:182980], also called late onset spinal muscular atrophy Finkel type. Spinal muscular atrophies are neurodegenerative disorders characterized by degeneration of lower motor neurons, leading to progressive paralysis muscular atrophy. This form is a late adult onset form of the disease (after age 20 years). The patients show a benign course, most of them remaining ambulatory 10 to 40 years after clinical onset.

Gen-ID: 9217

Pathways: ER-Nucleus Signaling