LONP1 Antikörper (AA 361-460) (Biotin)

Produktnummer ABIN705808

Produktdetails anti-LONP1 Antikörper (Biotin)

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Bindungsspezifität: AA 361-460

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LONP1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LONP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu LONP1

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Andere Bezeichnung: LONP1 (LONP1 Produkte)

Synonyme: PRSS15 antikoerper, prss15 antikoerper, fc64d11 antikoerper, wu:fc64d11 antikoerper, LON antikoerper, LONP antikoerper, LonHS antikoerper, PIM1 antikoerper, hLON antikoerper, 1200017E13Rik antikoerper, Prss15 antikoerper, Lon antikoerper, lon peptidase 1, mitochondrial antikoerper, ATP-dependent Lon protease antikoerper, LONP1 antikoerper, lonp1 antikoerper, Lonp1 antikoerper, PIM1 antikoerper

Hintergrund:

Synonyms: LON, LONP, hLON, LonHS, PRSS15, Lon protease homolog, mitochondrial, Lon protease-like protein, Mitochondrial ATP-dependent protease Lon, Serine protease 15, LONP1

Background: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.

Gen-ID: 9361

UniProt: P36776